Scientists at the University of Florida have created a breakthrough mRNA cancer vaccine that erased deadly brain tumors in early human trials without chemo or radiation. Tested on four glioblastoma patients, the vaccine reprogrammed their immune systems within 48 hours to attack the tumor. Built from each patient’s own tumor cells and delivered via lipid nanoparticles, it showed success similar to earlier tests in mice and dogs. It is now moving into Phase 1 pediatric trials.